Dr. Gary P. Lawton, MD, FACS

Training:

• Resident in Plastic Surgery
• Yale University School of Medicine
• New Haven, Connecticut
• 1997-2000

Honors:

• Corso Award for Plastic Surgery Research
• 1999 – 2000

Training:

• Chief Resident in General Surgery
• Yale University School of Medicine
• Surgical Research Fellow
• Gastrointestinal Pathobiology Research Group
• Yale University School of Medicine
• 1993- 1997

Honors:

• American College of Surgeons Scholarship for the Study of Wound Healing
• Ohse Foundation Research Fellowship
• Yale University Department of Surgery
• Scientific Presentation Award
• Association of VA Surgeons
• Scientific Presentation Award
• CT Society of American Board Surgeons
• 1993-1995

Training:

• Resident in General Surgery
• Yale University School of Medicine
• 1990-93

Education:

• Doctor of Medicine
• University of Massachusetts Medical School in Worcester, Massachusetts
• 1990

Honors:

• Senior Scholar in Surgery
• 1990

Education:

• Bachelor of Science, Chemical Engineering
• Minor: Chemistry
• University of Massachusetts at Amherst
• 1986

Honors:

• Summa cum laude
• Departmental Honors, Second in Class
• Tau Beta Pi Engineering Honor Society
• Phi Kappa Phi Honor Society
• Golden Key Honor Society
• 1985-1986

Publications:

• Lawton G.P., Ariyan S., Rasque H., Perez A. Relationship
  between fascia preservation and lymphedema after axillary
  and ilioinguinofemoral lymphadenectomy for melanoma. In
  Press
• Ariyan S., Lawton G.P. Regional Lymph Node Dissections
  In: Malignant Melanoma. Clinics in Plastic Surgery. W. B.
  Saunders Co. Philadelphia. In Press
• Lawton G.P., Tang L. H., Kidd M., Chinery R., Miu K.,
  Modlin I. M. Regulation of mastomys ECL cell function by
  transforming growth factor alpha. J Surg Research 1996,
  60(2):293-302.
• Lawton G.P., Tang L.H., Miu K., Gilligan C.J., Absood A.,
  Modlin I.M. Adrenergic and cromolyn sodium modulation of ECL
  cell histamine secretion. J Surg Research 1995, 58: 96-104.
• Lawton G.P., Modlin I.M. Recent advances in the
  localization and surgical management of duodenal
  gastrinomas. In: Current Opinion in General Surgery. Current
  Science, Philadelphia. 1994: 131-137.
• Modlin I.M., Lawton G.P. Duodenal gastrinoma: Solution
  to the pancreatic paradox. J Clin Gastroenterol 1994, 19:184-
  188.
• Modlin I. M., Lawton G.P., Begos D. J. The dumping
  syndrome and postvagotomy diarrhea. In : Nyhus L. M. (ed)
  Mastery of Surgery, Third Edition, Little Brown and Company,
  Boston 1997.
• Modlin I.M., Lawton G.P., Miu K., Kidd M., Luque E.A.,
  Sandor A., Tang L.H. Pathophysiology of the fundic
  enterochromaffin-like (ECL) cell and gastric carcinoid
  tumours. Ann R Coll Surg Engl 1996, 78:133-138.
• Modlin I. M., Lawton G.P. Observations on the Gallic
  Gastric Illuminati. Perspectives in Biology and Medicine
  1996, 39(4)527-543.
• Gilligan C.J., Lawton G.P., Tang L.H., West A.B.,
  Modlin I.M. Gastric carcinoid tumors: The biology and
  therapy of an enigmatic and controversial lesion. Am J
  Gastro 1995, 90: 338-352.
• Powers R. E., Lawton G.P., Modlin I. M. Genotoxicity and
  acid suppressing medications. Pharmacol and Therapeutics
  1995, 65:303-317
• Sgambati S., Lawton G.P., Modlin I.M. Chronic
  pancreatitis: A precursor to pancreatic carcinoma? Dig
  Surgery 1994, 11:275-285.
• Modlin I.M., Lawton G.P. Evolution of an operative
  strategy for diagnosis and management of duodenal
  gastrinomas. Journal of the American College of Surgeons.
  1994, 179: 611-625.
• Modlin I.M., Lawton G.P. The evolving clinical uses of
  octreotide. Drug Therapy 1994, 24: 28-38.
• Modlin I.M., Lawton G.P., Tang L.H., Geibel J., Abraham
  R., Darr U. The mastomys gastric carcinoid: Aspects of ECL
  cell function. Digestion 1994, 55: 31-37.
• Modlin I.M., Gilligan C.J., Lawton G.P., Tang L.H., West
  A.B. Observations on the relationship between
  hypergastrinemia, multiple gastric carcinoids, and a
  pancreatic mass. Dig Dis & Sci 1996, 41(1):105-114.
• Sandor A., Kidd M., Lawton G.P., Tang L. H., Miu K.,
  Modlin I. M. Neurohormonal modulation of rat
  enterochromaffin-like cell histamine secretion.
  Gastroenterology 1996, 110:1084-1092.
• Tang L.H., Modlin I.M., Lawton G.P., Kidd M., Chinery R.
  The role of transforming growth factor a in the
  enterochromaffin-like cell tumor autonomy in an African
  rodent Mastomys. Gastroenterology 1996, 111(5):1212-1223.
• Modlin I.M., Cornelius E., Lawton G.P. Use of an
  isotopic somatostatin receptor probe to image gut endocrine
  tumors. Archives of Surgery 1995, 130: 367-374.
• Modlin I.M., Gilligan C.J., Lawton G.P., Tang L.H., West
  A.B., Darr U. Gastric Carcinoids: The Yale experience.
  Archives of Surgery 1995, 130(3)1250-1255.
• Modlin I.M., Goldenring J.R., Lawton G.P., Hunt R.J.
  Aspects of the theoretical basis and clinical relevance of
  low acid states. American Journal of Gastroenterology 1994,
  89(3): 308-318.
• Modlin I.M., Tang L.H., Lawton G.P., Darr U., Zhu Z.H.,
  Soroka C.J. Enterochromaffin like cell pathobiology of
  mastomys. Annals of the New York Academy of Sciences 1994,
  733: 365-379.
• Kidd M., Tang L.H., Miu K., Lawton G.P., Sandor A.,
  Modlin I.M. Autoregulation of enterochromaffin-like cell
  histamine secretion via the histamine 3 receptor subtype.
  Yale J Biol and Med 1996, 69:9-19.
• Modlin I. M., Zhu Z. Z., Tang L. H., Kidd M., Lawton
  G.P., Miu K., Powers R. E. Goldenring J. R. Pasikov D.,
  Soroka C. J. Evidence for a regulatory role for histamine in
  gastric enterochromaffin-like cell proliferation induced by
  hypergastrinemia. Digestion 1996, 57:310-21.

Abstracts:

• Lawton G.P., Tang L.H., Miu K., Modlin I.M. The histamine
  and transforming growth factor alpha contribution to the
  mucosal mitogenic cascade induced by gastrin. The 19th
  Annual Surgical Symposium of the Association of VA Surgeons,
  Pittsburgh, PA, 1995.
• Modlin I. M, Lawton G.P., Tang L. H., Miu K., Schwartz J.
  C. Histamine-3 receptor modulation of ECL cell histamine
  secretion and DNA synthesis. American Gastroenterology
  Association, Abstract Supplement 1995, 108: A992 San Diego,
  CA, 1995.
• Tang L. H., Lawton G.P., Miu K., Modlin I. M. Alteration
  of the gastrin/CCK-B receptor by endogenous hypergastrinemia
  in transformed ECL cells. American Gastroenterology
  Association, Abstract Supplement 1995, 108:A1011 San Diego,
  CA, 1995.
• Modlin I. M., Lawton G.P., Tang L. H., Chinery R., Wright
  N. ECL cell TGFa production drives the gastrin-independent
  phase of ECL cell proliferation. American Gastroenterology
  Association, Abstract Supplement 1995, 108:A992 San Diego,
  CA, 1995.
• Cornelius E., Lawton G.P., Modlin I.M. Somatostatin
  receptor scintigraphy of tumors. Fifth Conference on
  Radioimmunodetection and Radioimmunotherapy of Cancer,
  Orlando, FL, 1995.
• Cornelius E., Shi C., Lawton G.P., Modlin I. M.
  Octreotide scintigraphy: Comparison with CT and MR. Society
  of Nuclear Medicine 42nd Annual Meeting, Minneapolis, MN,
  1995.
• Kidd M., Sandor A., Lawton G.P., Tang L. H., O’Keefe S.,
  Modlin I. M. The role of calcium channels in gastrin driven
  ECL cell histamine secretion. American Gastroenterology
  Association, Abstract Supplement 1995, 108:A627 San Diego,
  CA, 1995.
• Kidd M., Sandor A., Lawton G.P., Tang L. H., O’Keefe S.,
  Modlin I. M. Acetylcholine mediated enterochromaffin-like
  (ECL) cell modulation of the cephalic phase of acid
  secretion. American Gastroenterology Association, Abstract
  Supplement 1995, San Diego, CA, 1995.
• Sandor A., Kidd M., Lawton G.P., Tang L. H., O’Keefe S.,
  Modlin I. M. Neurotransmitter regulation of ECL cell
  histamine secretion. American Gastroenterology Association,
  Abstract Supplement 1995, San Diego, CA, 1995.
• Lawton G.P., Tang L.H., Miu K., Modlin I.M. Modulation
  of enterochromaffin-like cell histamine secretion via a ß-
  adrenergic mechanism and the mast cell inhibitor sodium
  cromoglycate. The 18th Annual Surgical Symposium of the
  Association of VA Surgeons, Reno, Nevada, 1994.
• Modlin I.M., Lawton G.P., Cornelius E.A.. The surgical
  utility of an isotopic somatostatin receptor probe to
  identify gut neuroendocrine tumors and their metastases. New
  England Surgical Society, Newport, RI, 1994.
• Modlin I.M., Lawton G.P., Gilligan C.J., Tang L.H., Darr
  U, West A.B. The relationship between hypergastrinemia,
  gastric carcinoids and gastric adenocarcinoma in humans. New
  England Surgical Society, Newport, RI, 1994.
• Modlin I.M., Zhu Z.,Powers R.E., Goldenring J.R., Tang
  L.H., Lawton G.P., Miu K., Soroka C. Tamoxifen modulated
  hypergastrinemia amplifies gastric carcinoid tumor
  generation. Association of Academic Surgeons, Albuquerque,
  NM, 1994.
• Modlin I.M., Lawton G.P., Gilligan C.J., Tang L.H., Darr
  U, West A.B. Gastric carcinoid: The Connecticut experience.
  Connecticut Society of American Board Surgeons, Cromwell,
  CT, 1994.
• Tang L. H., Lawton G.P., Darr U., Modlin I.M. Proton
  pump inhibition down regulates enterochromaffin-like cell
  function. American Gastroenterology Association, Abstract
  Supplement 1994, New Orleans, LA 1994.
• Modlin I. M., Cornelius E., Lawton G.P. Somatostatin
  analog scintigraphy in the localization of
  gastroenteropancreatic neuroendocrine tumors. Connecticut
  Society of American Board Surgeons, Cromwell, CT, 1994.
• Abraham R. G., Lawton G.P., Tang L. H., Darr U., Geibel
  J., Modlin I. M. ECL cell secretion is mediated by a
  calcium mechanism as characterized by both isolated cell and
  gland fluorescent video imaging and confocal microscopy.
  American Gastroenterology Association, Abstract Supplement
  1994, New Orleans, LA 1994.
• Biggs C., Lawton G.P., Tang L. H., Darr U., Modlin I.
  M. The cephalic phase of acid secretion may reflect
  cholinergic modulation of gastrin driven ECL cell histamine
  secretion. American Gastroenterology Association, Abstract
  Supplement 1994, New Orleans, LA 1994.
• Lawton G.P., Tang L.H., Miu K.,Darr U., Modlin I.M.
  Transforming growth factor alpha inhibits gastric
  enterochromaffin-like (ECL) cell secretion of histamine.
  Connecticut Society of American Board Surgeons, Cromwell,
  CT, 1994.
• Lawton G.P., Tang L.H., Saroka C., Darr U., Abraham R.,
  Modlin I.M. Characterization of isolated enterochromaffin-
  like cell function during parietal cell proton pump
  inhibition. Connecticut Society of American Board Surgeons,
  Cromwell, CT, 1993.
• Darr U., Lawton G.P., Abraham R.G, Modlin I.M. Gastric
  carcinoid: Enigma or entity. Connecticut Society of American
  Board Surgeons, Cromwell, CT, 1993.
• Abraham R.G., Giebel J., Tang L.H., Lawton G.P., Darr
  U., Soroka C.J., Modlin I.M. Evaluation of ECL cell
  secretory regulation utilizing image analysis of
  intracellular pH and calcium transients. Connecticut Society
  of American Board Surgeons, Cromwell, CT, 1993.

Presentations:

• 3-D anatomy of the malar fat pad. Yale Corso Award, 2000.
• Endoscopes in Plastic Surgery. Yale Plastic Surgery Grand
  Rounds, 1999.
• Structural anatomy of the midface. Yale Corso Award,
  1999.
• Relationship between fascia preservation and lymphedema
  after axillary and ilioinguinofemoral lymphadenectomy for
  melanoma. New England Society of Plastic and Reconstructive
  Surgeons, Newport, RI, 1999.
• Craniofacial trauma: Historical perspectives. Yale
  Plastic Surgery Grand Rounds, 1998.
• Controversies in replantation. Yale Plastic Surgery Grand
  Rounds, 1997.
• Humours, tumours, and rumours. Yale Surgery Grand Rounds,
  1997.
• Transforming growth factor a regulates enterochromaffin-
  like cell tumor autonomy. The Gut as a Model in Cell and
  Molecular Biology, Freiburg, Germany, 1996.
• Surgical approach to thyroid and parathyroid pathology.
  Department of Surgery, Yale University School of Medicine,
  Resident Lecture Series, 1996.
• The histamine and transforming growth factor alpha
  contribution to the mucosal mitogenic cascade induced by
  gastrin. Assoc of VA Surgeons, Pittsburgh, PA, 1995.
• Carcinoid as a model of growth regulation in
  neuroendocrine tumors. Department of Surgery, Yale
  University School of Medicine, Resident Lecture Series,
  1995.
• Tamoxifen modulated hypergastrinemia amplifies gastric
  carcinoid tumor generation. Association of Academic Surgeons
  25th Annual Meeting, Albuquerque, NM 1994.
• Modulation of ECL cell histamine secretion via a ß-
  adrenergic mechanism. Assoc of VA Surgeons, Reno, Nevada,
  1994. Scientific Presentation Award.
• Transforming growth factor alpha inhibits gastric
  enterochromaffin-like cell secretion of histamine. CT Soc of
  Am Board Surgeons, 1994. Scientific Presentation Award.
• Management priorities in maxillofacial trauma.
  Department of Surgery, Yale University School of Medicine,
  Resident Lecture Series, 1993.
• Gastric stromal tumors: Current pathological
  perspectives. Department of Surgery, Yale University School
  of Medicine, Resident Lecture Series, 1992.
• Physikos Oinodotes: History of the medicinal uses of
  wine. Department of Surgery, Yale University School of
  Medicine, Resident Lecture Series, 1991.