Training:

Resident in Plastic Surgery
Yale University School of Medicine
New Haven, Connecticut

1997-00

Honors: Corso Award for Plastic Surgery Research 1999, 2000
Training:

Chief Resident in General Surgery
Yale University School of Medicine

Surgical Research Fellow
Gastrointestinal Pathobiology Research Group
Yale University School of Medicine

1995-97

1993-95

Honors:

American College of Surgeons Scholarship
for the Study of Wound Healing

Ohse Foundation Research Fellowship
Yale University Department of Surgery

Scientific Presentation Award
Association of VA Surgeons

Scientific Presentation Award
CT Society of American Board Surgeons

1993-1995

1993,1994

1994

1994

Training:

Resident in General Surgery
Yale University School of Medicine

1990-93

Education:

Doctor of Medicine
University of Massachusetts Medical School
Worcester, Massachusetts

1990

Honors:

Senior Scholar in Surgery

1990

Education:

Bachelor of Science, Chemical Engineering
Minor: Chemistry
University of Massachusetts at Amherst

1986

Honors:

Summa cum laude
Departmental Honors, Second in Class
Tau Beta Pi Engineering Honor Society
Phi Kappa Phi Honor Society
Golden Key Honor Society

1986
1986
1985
1986
1986

Publications:

  1. Lawton G.P., Ariyan S., Rasque H., Perez A. Relationship
    between fascia preservation and lymphedema after axillary
    and ilioinguinofemoral lymphadenectomy for melanoma. In
    Press
  2. Ariyan S., Lawton G.P. Regional Lymph Node Dissections
    In: Malignant Melanoma. Clinics in Plastic Surgery. W. B.
    Saunders Co. Philadelphia. In Press
  3. Lawton G.P., Tang L. H., Kidd M., Chinery R., Miu K.,
    Modlin I. M. Regulation of mastomys ECL cell function by
    transforming growth factor alpha. J Surg Research 1996,
    60(2):293-302.
  4. Lawton G.P., Tang L.H., Miu K., Gilligan C.J., Absood A.,
    Modlin I.M. Adrenergic and cromolyn sodium modulation of ECL
    cell histamine secretion. J Surg Research 1995, 58: 96-104.
  5. Lawton G.P., Modlin I.M. Recent advances in the
    localization and surgical management of duodenal
    gastrinomas. In: Current Opinion in General Surgery. Current
    Science, Philadelphia. 1994: 131-137.
  6. Modlin I.M., Lawton G.P. Duodenal gastrinoma: Solution
    to the pancreatic paradox. J Clin Gastroenterol 1994, 19:184-
    188.
  7. Modlin I. M., Lawton G.P., Begos D. J. The dumping
    syndrome and postvagotomy diarrhea. In : Nyhus L. M. (ed)
    Mastery of Surgery, Third Edition, Little Brown and Company,
    Boston 1997.
  8. Modlin I.M., Lawton G.P., Miu K., Kidd M., Luque E.A.,
    Sandor A., Tang L.H. Pathophysiology of the fundic
    enterochromaffin-like (ECL) cell and gastric carcinoid
    tumours. Ann R Coll Surg Engl 1996, 78:133-138.
  9. Modlin I. M., Lawton G.P. Observations on the Gallic
    Gastric Illuminati. Perspectives in Biology and Medicine
    1996, 39(4)527-543.
  10. Gilligan C.J., Lawton G.P., Tang L.H., West A.B.,
    Modlin I.M. Gastric carcinoid tumors: The biology and
    therapy of an enigmatic and controversial lesion. Am J
    Gastro 1995, 90: 338-352.
  11. Powers R. E., Lawton G.P., Modlin I. M. Genotoxicity and
    acid suppressing medications. Pharmacol and Therapeutics
    1995, 65:303-317
  12. Sgambati S., Lawton G.P., Modlin I.M. Chronic
    pancreatitis: A precursor to pancreatic carcinoma? Dig
    Surgery 1994, 11:275-285.
  13. Modlin I.M., Lawton G.P. Evolution of an operative
    strategy for diagnosis and management of duodenal
    gastrinomas. Journal of the American College of Surgeons.
    1994, 179: 611-625.
  14. Modlin I.M., Lawton G.P. The evolving clinical uses of
    octreotide. Drug Therapy 1994, 24: 28-38.
  15. Modlin I.M., Lawton G.P., Tang L.H., Geibel J., Abraham
    R., Darr U. The mastomys gastric carcinoid: Aspects of ECL
    cell function. Digestion 1994, 55: 31-37.
  16. Modlin I.M., Gilligan C.J., Lawton G.P., Tang L.H., West
    A.B. Observations on the relationship between
    hypergastrinemia, multiple gastric carcinoids, and a
    pancreatic mass. Dig Dis & Sci 1996, 41(1):105-114.
  17. Sandor A., Kidd M., Lawton G.P., Tang L. H., Miu K.,
    Modlin I. M. Neurohormonal modulation of rat
    enterochromaffin-like cell histamine secretion.
    Gastroenterology 1996, 110:1084-1092.
  18. Tang L.H., Modlin I.M., Lawton G.P., Kidd M., Chinery R.
    The role of transforming growth factor a in the
    enterochromaffin-like cell tumor autonomy in an African
    rodent Mastomys. Gastroenterology 1996, 111(5):1212-1223.
  19. Modlin I.M., Cornelius E., Lawton G.P. Use of an
    isotopic somatostatin receptor probe to image gut endocrine
    tumors. Archives of Surgery 1995, 130: 367-374.
  20. Modlin I.M., Gilligan C.J., Lawton G.P., Tang L.H., West
    A.B., Darr U. Gastric Carcinoids: The Yale experience.
    Archives of Surgery 1995, 130(3)1250-1255.
  21. Modlin I.M., Goldenring J.R., Lawton G.P., Hunt R.J.
    Aspects of the theoretical basis and clinical relevance of
    low acid states. American Journal of Gastroenterology 1994,
    89(3): 308-318.
  22. Modlin I.M., Tang L.H., Lawton G.P., Darr U., Zhu Z.H.,
    Soroka C.J. Enterochromaffin like cell pathobiology of
    mastomys. Annals of the New York Academy of Sciences 1994,
    733: 365-379.
  23. Kidd M., Tang L.H., Miu K., Lawton G.P., Sandor A.,
    Modlin I.M. Autoregulation of enterochromaffin-like cell
    histamine secretion via the histamine 3 receptor subtype.
    Yale J Biol and Med 1996, 69:9-19.
  24. Modlin I. M., Zhu Z. Z., Tang L. H., Kidd M., Lawton
    G.P., Miu K., Powers R. E. Goldenring J. R. Pasikov D.,
    Soroka C. J. Evidence for a regulatory role for histamine in
    gastric enterochromaffin-like cell proliferation induced by
    hypergastrinemia. Digestion 1996, 57:310-21.

Abstracts:

  1. Lawton G.P., Tang L.H., Miu K., Modlin I.M. The histamine
    and transforming growth factor alpha contribution to the
    mucosal mitogenic cascade induced by gastrin. The 19th
    Annual Surgical Symposium of the Association of VA Surgeons,
    Pittsburgh, PA, 1995.
  2. Modlin I. M, Lawton G.P., Tang L. H., Miu K., Schwartz J.
    C. Histamine-3 receptor modulation of ECL cell histamine
    secretion and DNA synthesis. American Gastroenterology
    Association, Abstract Supplement 1995, 108: A992 San Diego,
    CA, 1995.
  3. Tang L. H., Lawton G.P., Miu K., Modlin I. M. Alteration
    of the gastrin/CCK-B receptor by endogenous hypergastrinemia
    in transformed ECL cells. American Gastroenterology
    Association, Abstract Supplement 1995, 108:A1011 San Diego,
    CA, 1995.
  4. Modlin I. M., Lawton G.P., Tang L. H., Chinery R., Wright
    N. ECL cell TGFa production drives the gastrin-independent
    phase of ECL cell proliferation. American Gastroenterology
    Association, Abstract Supplement 1995, 108:A992 San Diego,
    CA, 1995.
  5. Cornelius E., Lawton G.P., Modlin I.M. Somatostatin
    receptor scintigraphy of tumors. Fifth Conference on
    Radioimmunodetection and Radioimmunotherapy of Cancer,
    Orlando, FL, 1995.
  6. Cornelius E., Shi C., Lawton G.P., Modlin I. M.
    Octreotide scintigraphy: Comparison with CT and MR. Society
    of Nuclear Medicine 42nd Annual Meeting, Minneapolis, MN,
    1995.
  7. Kidd M., Sandor A., Lawton G.P., Tang L. H., O’Keefe S.,
    Modlin I. M. The role of calcium channels in gastrin driven
    ECL cell histamine secretion. American Gastroenterology
    Association, Abstract Supplement 1995, 108:A627 San Diego,
    CA, 1995.
  8. Kidd M., Sandor A., Lawton G.P., Tang L. H., O’Keefe S.,
    Modlin I. M. Acetylcholine mediated enterochromaffin-like
    (ECL) cell modulation of the cephalic phase of acid
    secretion. American Gastroenterology Association, Abstract
    Supplement 1995, San Diego, CA, 1995.
  9. Sandor A., Kidd M., Lawton G.P., Tang L. H., O’Keefe S.,
    Modlin I. M. Neurotransmitter regulation of ECL cell
    histamine secretion. American Gastroenterology Association,
    Abstract Supplement 1995, San Diego, CA, 1995.
  10. Lawton G.P., Tang L.H., Miu K., Modlin I.M. Modulation
    of enterochromaffin-like cell histamine secretion via a ß-
    adrenergic mechanism and the mast cell inhibitor sodium
    cromoglycate. The 18th Annual Surgical Symposium of the
    Association of VA Surgeons, Reno, Nevada, 1994.
  11. Modlin I.M., Lawton G.P., Cornelius E.A.. The surgical
    utility of an isotopic somatostatin receptor probe to
    identify gut neuroendocrine tumors and their metastases. New
    England Surgical Society, Newport, RI, 1994.
  12. Modlin I.M., Lawton G.P., Gilligan C.J., Tang L.H., Darr
    U, West A.B. The relationship between hypergastrinemia,
    gastric carcinoids and gastric adenocarcinoma in humans. New
    England Surgical Society, Newport, RI, 1994.
  13. Modlin I.M., Zhu Z.,Powers R.E., Goldenring J.R., Tang
    L.H., Lawton G.P., Miu K., Soroka C. Tamoxifen modulated
    hypergastrinemia amplifies gastric carcinoid tumor
    generation. Association of Academic Surgeons, Albuquerque,
    NM, 1994.
  14. Modlin I.M., Lawton G.P., Gilligan C.J., Tang L.H., Darr
    U, West A.B. Gastric carcinoid: The Connecticut experience.
    Connecticut Society of American Board Surgeons, Cromwell,
    CT, 1994.
  15. Tang L. H., Lawton G.P., Darr U., Modlin I.M. Proton
    pump inhibition down regulates enterochromaffin-like cell
    function. American Gastroenterology Association, Abstract
    Supplement 1994, New Orleans, LA 1994.
  16. Modlin I. M., Cornelius E., Lawton G.P. Somatostatin
    analog scintigraphy in the localization of
    gastroenteropancreatic neuroendocrine tumors. Connecticut
    Society of American Board Surgeons, Cromwell, CT, 1994.
  17. Abraham R. G., Lawton G.P., Tang L. H., Darr U., Geibel
    J., Modlin I. M. ECL cell secretion is mediated by a
    calcium mechanism as characterized by both isolated cell and
    gland fluorescent video imaging and confocal microscopy.
    American Gastroenterology Association, Abstract Supplement
    1994, New Orleans, LA 1994.
  18. Biggs C., Lawton G.P., Tang L. H., Darr U., Modlin I.
    M. The cephalic phase of acid secretion may reflect
    cholinergic modulation of gastrin driven ECL cell histamine
    secretion. American Gastroenterology Association, Abstract
    Supplement 1994, New Orleans, LA 1994.
  19. Lawton G.P., Tang L.H., Miu K.,Darr U., Modlin I.M.
    Transforming growth factor alpha inhibits gastric
    enterochromaffin-like (ECL) cell secretion of histamine.
    Connecticut Society of American Board Surgeons, Cromwell,
    CT, 1994.
  20. Lawton G.P., Tang L.H., Saroka C., Darr U., Abraham R.,
    Modlin I.M. Characterization of isolated enterochromaffin-
    like cell function during parietal cell proton pump
    inhibition. Connecticut Society of American Board Surgeons,
    Cromwell, CT, 1993.
  21. Darr U., Lawton G.P., Abraham R.G, Modlin I.M. Gastric
    carcinoid: Enigma or entity. Connecticut Society of American
    Board Surgeons, Cromwell, CT, 1993.
  22. Abraham R.G., Giebel J., Tang L.H., Lawton G.P., Darr
    U., Soroka C.J., Modlin I.M. Evaluation of ECL cell
    secretory regulation utilizing image analysis of
    intracellular pH and calcium transients. Connecticut Society
    of American Board Surgeons, Cromwell, CT, 1993.

Presentations:

  1. 3-D anatomy of the malar fat pad. Yale Corso Award, 2000.
  2. Endoscopes in Plastic Surgery. Yale Plastic Surgery Grand
    Rounds, 1999.
  3. Structural anatomy of the midface. Yale Corso Award,
    1999.
  4. Relationship between fascia preservation and lymphedema
    after axillary and ilioinguinofemoral lymphadenectomy for
    melanoma. New England Society of Plastic and Reconstructive
    Surgeons, Newport, RI, 1999.
  5. Craniofacial trauma: Historical perspectives. Yale
    Plastic Surgery Grand Rounds, 1998.
  6. Controversies in replantation. Yale Plastic Surgery Grand
    Rounds, 1997.
  7. Humours, tumours, and rumours. Yale Surgery Grand Rounds,
    1997.
  8. Transforming growth factor a regulates enterochromaffin-
    like cell tumor autonomy. The Gut as a Model in Cell and
    Molecular Biology, Freiburg, Germany, 1996.
  9. Surgical approach to thyroid and parathyroid pathology.
    Department of Surgery, Yale University School of Medicine,
    Resident Lecture Series, 1996.
  10. The histamine and transforming growth factor alpha
    contribution to the mucosal mitogenic cascade induced by
    gastrin. Assoc of VA Surgeons, Pittsburgh, PA, 1995.
  11. Carcinoid as a model of growth regulation in
    neuroendocrine tumors. Department of Surgery, Yale
    University School of Medicine, Resident Lecture Series,
    1995.
  12. Tamoxifen modulated hypergastrinemia amplifies gastric
    carcinoid tumor generation. Association of Academic Surgeons
    25th Annual Meeting, Albuquerque, NM 1994.
  13. Modulation of ECL cell histamine secretion via a ß-
    adrenergic mechanism. Assoc of VA Surgeons, Reno, Nevada,
    1994. Scientific Presentation Award.
  14. Transforming growth factor alpha inhibits gastric
    enterochromaffin-like cell secretion of histamine. CT Soc of
    Am Board Surgeons, 1994. Scientific Presentation Award.
  15. Management priorities in maxillofacial trauma.
    Department of Surgery, Yale University School of Medicine,
    Resident Lecture Series, 1993.
  16. Gastric stromal tumors: Current pathological
    perspectives. Department of Surgery, Yale University School
    of Medicine, Resident Lecture Series, 1992.
  17. Physikos Oinodotes: History of the medicinal uses of
    wine. Department of Surgery, Yale University School of
    Medicine, Resident Lecture Series, 1991.